Published in The Spike·PinnedYour Cortex Contains 17 Billion ComputersNeural networks of neural networks — Brains receive input from the outside world, their neurons do something to that input, and create an output. That output may be a thought (I want curry for dinner); it may be an action (make curry); it may be a change in mood (yay curry!). Whatever the output, that “something”…Artificial Intelligence9 min read
Published in The Spike·Dec 21, 20212021: the review of the year in neuroscienceWelcome back my friends, to the show that never ends — It’s the most wonderful time of the year. Chiefly because neuroscience stops churning out new stuff and we get to draw breath before plunging anew into the maelstrom. …Neuroscience11 min read
Published in Elemental·Nov 22, 2021Her Depression Was Untreatable — Until Two Electrodes Were Implanted in Her BrainHow researchers are changing the brain’s messaging system to tackle mental health disorders — There’s a disturbingly long list of ways in which the brain can go wrong. I might name for you a sample of mental health conditions: schizophrenia, bipolar disorder, clinical depression, anxiety disorders of all kinds, obsessive compulsive disorder. Even just the list of movement disorders is miserably long: Parkinson’s disease…Science6 min read
Published in The Spike·Oct 20, 2021Maps of a Growing Brain Show That Genes Do Less Than We ThoughtThe worm turns against genetic determinism — There’s a strangely persistent idea that your genes are the blueprint for your brain. Robert Plomin even called his book about the genetic influence on the mind “Blueprint”. But a blueprint is a detailed one-to-one schematic of what will be constructed. Genes are not that. Self-evidently not. For example, people…Science5 min read
Published in Elemental·Jun 3, 2021The Absurdity of Peer ReviewWhat the pandemic revealed about scientific publishing — I was reading my umpteenth news story about Covid-19 science, a story about the latest research into how to make indoor spaces safe from infection, about whether cleaning surfaces or changing the air was more important. And it was bothering me. Not because it was dull (which, of course, it…Science8 min read
Published in OneZero·May 5, 2021We Can’t Upload You, SorryWhy we can’t put your mind in the machine — Immortality awaits. As you draw your dying breath, we will inject a preservative into your brain that will fix in place every one of the trillion or so connections between your 86 billion neurons. We will then trace those wires, building the complete map of your brain’s connections, your “connectome”…Science6 min read
Published in The Spike·Mar 16, 2021Why I Wrote a Book About SpikesIt’s how your brain works, after all — Neurons. Over the deep time of Earth’s history, these tiny bags of chemicals have joined forces, swarming together in gargantuan numbers, all to make a brain. In cahoots, these neurons do everything you do: sense, think, move; sleep, dream, and cogitate. Eat cake. Watch telly. …Neuroscience5 min read
Published in The Spike·Mar 9, 2021The Spike: the brain’s own languageHi everyone, as it’s our first newsletter, I just wanted to say a big thank you to you all for following us at The Spike on Medium. I’m so excited! Today sees the launch of my new book “The Spike: An Epic Journey Through the Brain in 2.1 Seconds” from…Neuroscience2 min read
Published in The Spike·Mar 8, 2021Now We Can Record One Million Neurons At The Same TimeA Dialogue — Have you heard? Scientists at Rockefeller University have just announced they can record one million individual neurons in the cortex of a mouse — at the same time! Wow, one million. Is that a lot? We got very excited about being able to record 10,000 neurons in the mouse brain…Neuroscience6 min read
Published in The Spike·Feb 23, 2021The Spike: An Epic Journey Through the Brain in 2.1 SecondsMy new book about your life in spikes — Your life is lived in spikes. Your brain uses electricity to communicate, its neurons talking to each other by sending tiny pulses of voltage down a gossamer thin cable. We neuroscientists call those pulses “spikes”. …Neuroscience5 min read